Botox was FDA approved in 1989 for muscular spasms. In 1992, it was discovered to have a wrinkle relaxing effect when used In the upper face, and it received full FDA approval for frown line treatment in 2002. Dysport was soon approved afterwards in 2009, and most recently Jeuveau in 2019. All of these products are safe, effective, and have many years of clinical research and patient safety behind them. Botox has become common in the public’s vocabulary to include all brands – much like Kleenex has become the recognizable word for all brands of facial tissue.